Tell us when you're flying home before you tell us what you want. It changes the answer. Where a treatment sits in your trip matters more than which one you pick.
Just arrived in Tokyo?
Hydra Gentle Dermashio
Refresh your skin after the flight.
During your trip?
Hydra Gentle Dermashio
Minimal downtime. Get back to Tokyo right after.
Flying home soon?
Botulinum toxin
Treat now. Results develop after you get home.
Swipe
02What we offer
Three treatments. That's it.
We could list forty. These are the three that work around a trip, so they're the only ones on this page.
Hydra Gentle
Best for
Pores / blackheads / rough texture
Downtime
< 1 day
Makeup
Same day
Price
¥14,500
Dermashio
Best for
Dryness / dullness / pigmentation
Downtime
Minimal
Makeup
Immediately
Price
¥16,500
Botulinum toxin
Best for
Expression lines
Downtime
Minimal
Results
≈ 1 week
Price
¥15,000 / area + fee
Most popular
Hydra Gentle + Dermashio
¥30,000
Combined, first visit — save ¥1,000
Downtime
after treatment
Hydra Gentle
Dermashio
Botulinum
Redness
< 1 day
Barely any
—
Swelling
Slight, if any
Barely any
A few days
Bruising
Possible
—
~4% 1–2 wks
Makeup
Same day
Straight away
Straight away
Fly after
Same day
Same day
≈4 hours
Hydra Gentle's redness and swelling are the usual course for this type of facial, not a measurement taken here.
On makeup after botulinum toxin: there is no fixed waiting time. Put it back on when you like — apply it gently, and avoid pressing or rubbing the injected areas for the rest of the day.
01
Hydra Gentle
Hydrodermabrasion facial
Main risks
Redness and stinging during treatment. Dryness, tightness or light flaking for a few days. Pinpoint red spots or bruising where the suction head passes (more likely on thin skin). Increased sun-sensitivity for several days. Less often: irritation or allergic reaction to a solution. Rarely: cold sore recurrence if you're prone to them.
We can't treat you if you are
Pregnant, possibly pregnant or breastfeeding · pacemaker or implanted defibrillator · severe diabetes, malignancy, heart disease, bleeding disorder or keloid-scarring tendency · active infection or severe dermatitis at the treatment site.
Three passes in one session: AHA lifts surface debris, BHA clears the pores, then hyaluronic acid goes back in.
60–90 min on a first visit — 30–60 min with the doctor, then about 30 min for the treatment itself
Course
Every 2–4 weeks, 5–10 sessions recommended
Washing, showering and makeup are fine same-day. Skip alcohol, hard exercise, baths and saunas that day, and limit sun exposure after. Redness/swelling figures are the usual course for this facial, not a clinic measurement — yours may differ.
What it feels like
A scratchy, stinging feeling as the handpiece passes, and a light tug from the suction. Skin feels tight and looks pink afterwards. Tell us any time and we'll ease off.
This is not HydraFacial®. Hydra Gentle is a different device.
02
Dermashio
Needle-free infusion · electroporation
Main risks
Tingling and warmth during treatment. Redness and itching afterwards, usually brief. Less often: dryness, small blisters, hives where the applicator sits, or a brief muscle twitch. Uncommon but serious: a superficial burn (if the current is too strong or skin is broken), or an allergic reaction to an infused ingredient — this treatment carries actives past the skin barrier, so a reaction is possible even to something you've used before.
We can't treat you if you have
A pacemaker, implanted defibrillator or any implanted electronic device — absolute. Also: pregnancy or possible pregnancy · epilepsy or seizure history · heart condition or abnormal rhythm · metal implants or surgical metalwork near the area · broken, infected, inflamed or sunburned skin there, or reduced sensation · known allergy to any serum.
Electrical pulses open temporary micro-channels, so actives reach the dermis. What used to need a needle goes in without one.
What it's for
Rough or dry skin, pigmentation, fine lines, laxity, dullness, acne
Time in clinic
60–90 min on a first visit — 30–60 min with the doctor, then about 30 min for the treatment itself
Base, always included
16 amino acids + 3 ceramides, and a high-performance vitamin C derivative (APPS + APS)
Mild but noticeable: a tingle, sometimes a metallic taste (the current reaching taste receptors — documented and harmless) or a flicker of light near the eyes (a phosphene, from the current reaching the retina — not considered harmful). Both stop the moment the current does. Thinner skin (forehead, cheeks) feels it more. Tell us any time and we'll turn it down.
Before you arrive: come with a clean face if you can, and take off any metal — necklaces, earrings, piercings.
03
Botulinum toxin injection
Expression lines
Main risks
Headache · heaviness or an odd feeling around the eyes · drooping brow or eyelid · pain, inflammation, redness, itching, swelling or bruising at the injection site. Rarely, the effect spreads beyond the site — see below.
We can't treat you if you are
Rare, but you should know
The effect can occasionally spread beyond the injection site. If you have difficulty swallowing, speaking or breathing, or unusual muscle weakness — any time in the following weeks, including once you're home — get medical help immediately, mention the botulinum toxin injection, then message us.
Regulatory disclosure — unapproved medicine
Not approved in Japan. We use Botulax (Hugel Inc., Republic of Korea), botulinum toxin type A — unapproved under Japan's Pharmaceuticals and Medical Devices Act.
How we obtain it: personal import by the physician. Medicines imported this way aren't assessed for quality, efficacy or safety under Japanese law, and fall outside Japan's adverse-drug-reaction relief system.
An approved equivalent exists here: Botox Vista (AbbVie GK) — same active ingredient, approved for glabellar and crow's-feet lines under 65. Distribution is controlled; the physician must complete the maker's training course. Other areas fall outside that indication.
Approved abroad, under another name. Korea 2009; the US (2024, glabellar lines only), EU, UK, China and Canada — all as Letybo, not Botulax. US boxed warning: the toxin can spread from the injection site, hours to weeks later. Swallowing and breathing difficulties can be life-threatening, and deaths have been reported. US trial adverse reactions: headache 2%; brow ptosis, eyelid ptosis, blepharospasm each under 1%. UK, August 2025: the MHRA listed Botulax among Korean brands not authorised in the UK, and seized stock. Japan: not approved here, so its safety and efficacy have not been established under Japanese review.
Relaxes the muscles that fold the skin. It doesn't work instantly, which for a trip is usually an advantage.
Forehead
¥15,000
Chin
¥15,000
Mouth corners
¥15,000
Procedure fee
¥5,000, once per visit — regardless of how many of the above areas you have treated
Anaesthetic
¥2,200 per area, optional
Time in clinic
About 60 min on a first visit — about 30 min with the doctor, then about 30 min for the injections
Onset
Noticeable at about 1 week, settled at 2 weeks
Lasts
Usually 3–4 months, then fades back gradually
Like any injection there's some swelling and soreness at the sites for a few days.
What it feels like
A quick sting at each injection point — the clinic describes it as little pain. Numbing cream available at ¥2,200 per area if you'd rather.
About bruising
Roughly 4% of injections, peaking a day or two later and clearing in one to two weeks — waiting an extra day before you fly doesn't avoid it. Concealer covers it.
Flying afterwards
No evidence-based waiting period exists — the 2016 international consensus found none supporting air-travel restrictions. As a practical precaution we suggest at least 4 hours, staying upright. Clinics abroad that say 24–48 hours are following convention, not a guideline.
Ask to see the box. We'll show you the sealed, batch-numbered packaging before anything is drawn up. Please do ask.
03Why oneUPclinic
Built to be easy for visitors.
No tourist surcharge
You pay exactly what someone living in Tokyo pays. The price on this page is the price at the desk.
Downtime in hours, not adjectives
Redness, bruising, makeup, flying: where there's a figure worth standing behind, you get the figure. Where there isn't, we say so.
Aftercare doesn't stop at the airport
Short appointments that leave your day intact. English instructions, a summary for your doctor at home, and a real person to message once you're back.
04Pricing
What you'll actually pay.
No tourist surcharge. Visitors to Japan pay exactly what residents pay.
Flat prices, tax and English aftercare instructions included. No per-unit billing, no upgrade at the desk. A first-visit consultation fee of ¥2,200 is charged once, on your first appointment. Botulinum toxin adds a one-time ¥5,000 procedure fee, regardless of how many areas you have treated.
Hydra Gentle
¥14,500
Dermashio
¥16,500
Hydra Gentle + Dermashiocombined
¥30,000save ¥1,000
Botulinum toxinforehead, chin or mouth corners
¥15,000per area, + ¥5,000 procedure fee
First-visit consultation feeonce, on your first appointment
¥2,200
Payment
Cash and credit card. Cards accepted: VISA, Mastercard, JCB, American Express, Diners Club.
If you need to cancel
Free up to noon the day before. After that, ¥3,300.
Any figure shown in your own currency elsewhere on this site is a reference only. Rates move, and everything is billed in Japanese yen.
05Who'll treat you
Dr. Toshio Sasai
Medical Director, oneUPclinic
Graduated from St. Marianna University School of Medicine in 2015; in clinical practice since, running oneUPclinic in Shimokitazawa.
Mostly aesthetic dermatology for skin texture — electroporation and pore-cleansing facials, two of the treatments here — plus hyaluronic acid, dermatologic lasers and HIFU, with the plan built around the skin in front of him.
Many patients are having an aesthetic treatment for the first time — the consultation is built for that.
06How it works
From your first message to your flight home.
Message us with your travel dates
WhatsApp or email. Online booking closes 24 hours ahead, so don't leave it to the morning of.
We confirm what's available
And send you an intake form in English before you arrive.
Come in
You see the doctor first, then have the treatment in the same visit. Not automatic: if that day isn't right, we say so and rebook.
Aftercare, including once you're home
Instructions in English, a summary for your doctor back home, and someone to message after you fly.
You're in charge of how far you go. Change your mind at the consultation, do less than planned, or skip treatment altogether. It costs nothing.
If you just want to see the calendar
Open the booking calendar to see what's open. It runs in Japanese and can't complete a first appointment on its own — message us and we'll do the booking for you.
07Before you book
What we'll tell you upfront.
Who we can't treat, and the risks for each treatment, are set out with that treatment above.
If you're flying soon after
Hydra Gentle and Dermashio: no waiting period, fly the same day. Botulinum toxin: at least four hours, staying upright.
Cabin air is dry (10–20% humidity) — bring a moisturiser. Don't press on your face: no eye mask, no neck pillow, no sleeping face-down. After Hydra Gentle, skin is more UV-sensitive for a few days, so keep the window shade down.
After botulinum toxin
Makeup can go straight back on — apply gently, and don't press, rub or massage the injected areas that day.
What to bring, and if something comes up
Your passport. For Dermashio, leave jewellery at the hotel. Worried after you fly home? Message us.
08Getting here
Four minutes from Shimokitazawa Station.
Shimokitazawa is two stops from Shibuya. You will almost certainly pass through it anyway.
From Shibuya
3 minKeio Inokashira Line, express or local — both stop here. About every 4 minutes.
From Shinjuku
7 minOdakyu Line, rapid express. Note the Romancecar does not stop at Shimokitazawa.
From Haneda (HND)
About 60 minKeikyu to Shinagawa, JR Yamanote to Shibuya, then the Inokashira Line.
From Narita (NRT)
About 1 hr 35 minNarita Express to Shibuya, then the Inokashira Line — one change.
Look for
Garden Terrace Shimokitazawa, ground floor, unit H — the clinic is on the north side of the station, on the Ichibangai shopping street side
Walking times are from Shimokitazawa Station (4 min from us). We don't book these and get nothing from them — just useful to know what's close.
Mustard Hotel Shimokitazawa
6 min walkDesign hotel, opened 2021
Yuen Bettei Daita
8 min walkOnsen ryokan — or 30 seconds from Setagaya-Daita, one stop away
The Wardrobe Hostel Forest
1–2 min walkHostel, dorms and private rooms
Shimokitazawa is a good place to spend the rest of your afternoon. Vintage shops, coffee, small live venues, and very few tour buses.
09FAQ
Questions we get a lot.
No. The consultation is held in English.
One thing to plan around: our online booking system runs in Japanese, so message us and we'll handle the booking for you.
Yes, and we'd prefer it. Message us with your travel dates and we'll confirm what's available before you commit to anything. Online slots close 24 hours ahead, and each month's slots open on the 15th of the month before.
Usually yes. First appointments here are booked as a consultation plus treatment in the same visit, so you don't need to come twice.
It isn't automatic. If what the doctor finds means treating you that day isn't the right call, we'll say so and rebook rather than proceed.
About 60 to 90 minutes on a first visit — 30 to 60 minutes with the doctor, then about 30 minutes for the treatment. Botulinum toxin is at the shorter end, around an hour in total.
After Hydra Gentle or Dermashio, yes — same day, no waiting period.
After botulinum toxin there's no evidence-based mandatory wait; we suggest at least four hours, staying upright. Bruising, if it happens, tends to show up a day or two later rather than immediately, so timing your flight doesn't change the odds. Your doctor confirms this at your consultation.
No. You pay what someone living in Tokyo pays. A first-visit fee of ¥2,200 is charged once, on your first appointment. The only other addition is on botulinum toxin, which carries a one-time ¥5,000 procedure fee regardless of how many areas you have treated.
VISA, Mastercard, JCB, American Express and Diners Club.
Free until noon the day before. After that there's a ¥3,300 cancellation fee. If your flight moves, tell us as early as you can and we'll work around it.
Japanese medical advertising rules restrict them, and ban patient testimonials outright. A before-and-after image may only run alongside the full treatment details, cost and risks for that case.
So instead of other people's results, this page tells you exactly what happens, what it costs, and what can go wrong.
Almost certainly not. These are elective, self-pay treatments. Check with your insurer if you're unsure, but plan on paying yourself.
Your passport.
10Get in touch
Ready when you are.
Message us with your travel dates and we'll take it from there.
